For example, Aire‐deficient mice are reported to exhibit multi‐organ autoimmunity characterised by autoantibodies and lymphocytic infiltrates against target tissues including the liver, pancreas, salivary gland and testis,[21, 46] correlating with autoimmune features characteristic of Autoimmune polyendocrinopathy‐candidiasis‐ectodermal dystrophy (APECED) in human patients driven by mutations in AIRE. The gene discussed is AIRE; the disease is Autoimmunity.