Furthermore, the results of the least absolute shrinkage and selection operator (LASSO) regression analysis indicated that the optimal model was developed when lambda was 0.058, and the 9 ERDEGs (PDIA4, GNS, OSMR, MXRA8, PDLIM4, STC1, C9orf64, SLC16A13, and GZMB) were prognosis-related genes (PRGs) of GBM patients (Figure 3B, 3C). This evidence concerns the gene GNS and glioblastoma.