The mechanisms of cuproptosis involve the gene models of copper homeostasis dysregulation, including cuproptosis regulator MTF1 (metal-regulatory transcription factor 1), the copper exporters ATP7A (ATPase copper-transporting alpha) and ATP7B (ATPase copper-transporting beta), which are encoded by genes that are mutated in the copper dysregulation syndrome Wilson’s disease [58, 59]. Here, ATP7A is linked to Wilson disease.