A sectorial/antigenic classification of immune-mediated neuropathies has been proposed based on the involved domain(s) of the myelinated fiber, and, when known, the target antigen.17For instance, antibodies against neurofascin-140/186 (in the node) or neurofascin-155 or contactin-1 (both in the paranode) could produce a clinical picture resembling CIDP, whereas antibodies against GM1 (in the node-paranode) could be associated with either acute motor and sensory axonal neuropathy or multifocal motor neuropathy. Here, CNTN1 is linked to chronic inflammatory demyelinating polyradiculoneuropathy.