The analysis revealed that lack of adsA in S. aureus phenocopied the Casp9 mutation in the host as adsA mutant-derived abscesses were also characterized by infiltrates of F4/80-positive phagocytes, irrespectively of whether animals expressed the Tie2-driven Cre recombinase or not (Fig 4I–4P). This evidence concerns the gene RNF170 and abscess.