CD4 and cancer: To investigate the connections between VRK1 and cancer immunity, we next analyzed the relationships between VRK1 expression and immune cell infiltration, including CD8+ T cells, CD4+ T cells, Tregs, B cells, monocytes, macrophages, NK cells, dendritic cells, mast cells, CAFs, progenitors, Endo cells, HSC, Tfh cells, γ/δ T cells, NKT cells, MDSCs, neutrophils (Figure 5).