Additionally, our findings revealed positive correlations between VRK1 expression and tumor mutation burden (TMB) in various cancer types, including BLCA, BRCA, COAD, GBM, HNSC, LGG, LUAD, LUSC, OV, PAAD, PCPG, PRAD, SARC, SKCM, and STAD. Here, VRK1 is linked to cancer.