This hypothesis is supported by Clausen et al. (2010, 2012) and Olsen et al. (2013), who showed that the use of antioxidants such as CAT mimetics in mice corrects or mitigates cognitive deficits and fear-conditioning deficits caused by oxidative stress and stimulates synaptic plasticity by taking part in neurotransmission. The gene discussed is CAT; the disease is Cognitive impairment.