TNF and metabolic dysfunction-associated steatohepatitis: High histidine‐rich glycoprotein expression in patients with NASH has been associated with disease staging,14 and several studies have demonstrated that lipotoxic hepatocytes release extracellular vesicles containing CXC chemokine ligand 10 and tumor necrosis factor (TNF)‐related apoptosis‐inducing ligand (also known as TNF superfamily member 10), which promote macrophage recruitment and activation and NAFLD progression.16, 17, 18