Many tumors exhibit fragmented mitochondria with upregulated DRP1 and decreased expression levels of MFN1 and MFN2255 in ovarian cancer,256 HCC,257 lung cancer,258 colon cancer,259 breast cancer,252 neuroblastoma,260 and glioblastoma,253 which are correlated to the metastatic potential of cancer cells. The gene discussed is MFN1; the disease is breast cancer.