The findings indicate that individuals with overweight/obesity (OW/OB) had significantly higher levels of body mass index (BMI), waist-to-hip ratio (WHR), FAT (%), systolic blood pressure (SBP), diastolic blood pressure (DBP), triglyceride (TG), free fatty acid (FFA), fasting blood glucose (FBG), 2 h blood glucose after glucose overload (2 h-BG), fasting insulin (FIns), 2 h insulin after glucose overload (2 h-Ins), HOMA-IR, the area under the curve for glucose (AUCg), the area under the curve for insulin (AUCi), and HbA1c, compared to the control group. Here, INS is linked to obesity due to melanocortin 4 receptor deficiency.