LAMP3 and non-small cell lung carcinoma: TLSs are immune cells capable of an anti-tumor immune response (TFH cells, follicular B cells, DC-LAMP+ mature dendritic cells, etc.), and their formation indicates the presence of continuous anti-tumor T and B cell immune responses at the tumor site; thus, their abundance and maturity can reflect the immune infiltration status of patients with NSCLC (20).