From the KEGG enrichment analysis, the top KEGG terms were related to Lipid and atherosclerosis, TNF signaling pathway, PI3K-Akt signaling pathway, HIF-1 signaling pathway, Toll-like receptor signaling pathway, MAPK signalling pathway and EGFR tyrosine kinase inhibitor resistance. The gene discussed is AKT1; the disease is atherosclerosis.