ADIPOQ and obesity disorder: By stimulating browning, energy expenditure, glucose uptake, adiponectin secretion, and fatty acid oxidation, it simultaneously suppresses lipogenesis, lipolysis, and pro-inflammatory markers in adipose tissue.(53,54) As a result, purslane activates AMPK to protect against obesity and metabolic dysfunction associated with it.(55,56) In addition, purslane supplementation has been associated with a reduction in the growth and differentiation of adipocytes, as well as an increase in lipolysis and fatty acid oxidation,(57) both known to suppress adipocytes.