By stimulating browning, energy expenditure, glucose uptake, adiponectin secretion, and fatty acid oxidation, it simultaneously suppresses lipogenesis, lipolysis, and pro-inflammatory markers in adipose tissue.(53,54) As a result, purslane activates AMPK to protect against obesity and metabolic dysfunction associated with it.(55,56) In addition, purslane supplementation has been associated with a reduction in the growth and differentiation of adipocytes, as well as an increase in lipolysis and fatty acid oxidation,(57) both known to suppress adipocytes. Here, ADIPOQ is linked to obesity due to melanocortin 4 receptor deficiency.