Specifically, the Grade 3 (25 to <50 × 109/l) category, which had a single study representation, exhibited a mean platelet count increase post-TPO-RA administration of 51.50 ± 13.60 × 109/l (95% CI = 37.90, 65.10) while two studies categorised under Grade 4 thrombocytopenia (<25 × 109/l) had a mean platelet count increase post-TPO-RA administration at 76.83 ± 382.14 × 109/l (95% CI = −305.31, 458.96). Here, TPO is linked to Thrombocytopenia.