We observed a strong negative correlation between EGFR_Y1068 abundance and afatinib response as quantified by the area under the curve (AUC, smaller AUC corresponds to higher sensitivity) across the eight liver cancer cell lines (R=−0.79,p=0.021, spearman correlation, Fig. 8D), suggesting that EGFR_Y1068 levels could be a potential marker of response to EGFR inhibition. The gene discussed is EGFR; the disease is liver cancer.