ATXN3 and early-onset autosomal dominant Alzheimer disease: Lavado cocoaextracts, and in particular their polyphenolic fraction, showed potentantiamyloidogenic activity against the Aβ1–42 peptide,a hallmark of Alzheimer’s disease.15 For these reasons, we tested the efficacy of our cocoa extractsagainst ATX3 protein aggregation and toxicity.