NCAM1 and in situ carcinoma: The ssGSEA analysis showed that the infiltration levels of Activated dendritic cell, Immature dendritic cell, Macrophage, Mast cell, MDSC, Neutrophil, Plasmacytoid dendritic cell and Regulatory T cell in CIS group were higher than that in control group, while the infiltration level of Activated B cell, CD56 bright natural killer cell, Immature B cell, Monocyte, Natural killer cell and T follicular helper cell in CIS group was lower (Figure 6A).