GATA1 and myelodysplastic syndrome: Our results demonstrate that Gata1 mRNA expression is increased in sorted bone marrow ProE, borderline decreased in BasoE, and decreased in PolyE and OrthoE erythroblasts from MDS relative to WT mice (Figure 4A–D), consistent with expectations that GATA1 expression is elevated in MDS patient bone marrow stem and progenitor and early erythroblasts (Maratheftis et al., 2007) with loss of upregulation during erythroblast differentiation (Hopfer et al., 2012).