NPHS1 and preeclampsia: After a multivariate analysis to control for possible confounders such as age, parity, and BMI (Table 2), for every unit increase in urinary nephrin levels, the odds of preeclampsia increased by about ninefold in the study participants (adjusted Odds ratio = 8.9, 95% CI: 2.8-29.2, P < 0.001).