STING1 and head and neck squamous cell carcinoma: To compare our data with the effect of IR on the STING-dependent ISG expression in a different cell type, we re-analyzed a publicly available RNA-Seq dataset (GSE147085) with wild-type and STING-knockout FaDu human head and neck squamous cell carcinoma cells, exposed to 4 fractions of 2 Gy doses of X-ray (67) using TEcount software (68, 69) (Supplementary Tables 3, 4).