RPS6 and neoplasm: It is also reassuring that stabJGL identifies many relevant tumor type-specific proteins as hubs in the relevant tumor type only, such as mammalian target of rapamycin (mTOR), Tuberous Sclerosis Complex 2, and Ribosomal protein S6 in BRCA, all of which are involved or up/downstream of the PI3K/AKT/mTOR pathway known to frequently be deregulated in Luminal BRCA (Miricescu et al. 2020).