According to the ROC curve analysis of ADAMTS9-AS2, the AUC value of plasma ADAMTS9-AS2 for diagnosing NSCLC is 0.957, and the sensitivity (95%) and specificity (99.1%) of plasma ADAMTS9-AS2 for diagnosing NSCLC are higher than those of CYFRA 21-1 (61.3% sensitivity and 60% specificity). Here, ADAMTS9 is linked to non-small cell lung carcinoma.