Further analysis by IHC of 16 normal cervix, 6 cases of cervical precancerous lesions (CIN‐III) and 42 cases of cervical cancer showed that the expression of TGFA protein in tumour tissues was higher than that in normal cells, while there was no significant increase in precancerous lesions, indicating that TGFA may play a role in cervical cancer transformation. The gene discussed is TGFA; the disease is cervical squamous intraepithelial neoplasia.