IGHE and allergic disease: In addition, the type ofallergen that the patient was sensitive to (confirmed by thepositivity of skin prick test and/or positivity ofallergen-specific IgE), sensitization status for inhaled allergens(monosensitized/polysensitized), type of allergen used duringimmunotherapy (pollen, house dust mite, pollen + house dust mite,cat and venom), immunotherapy treatment protocol (conventional/clustered), type of allergic reaction (LR, LLR, SR) and thedevelopment period (build-up phase/maintenance phase) and timing(immediate onset/delayed onset) of the allergic reaction wererecorded.