Rearrangement of NUMA1 with a protein tyrosine kinase or other partners (PDGFRB, ALK and RARA) has been previously reported only in a handful of haematological and mesenchymal tumours [11–13], but to the best of our knowledge, NUMA1 as an NTRK fusion partner has not been reported thus far in NTRK-rearranged uterine sarcomas or any other NTRK-rearranged tumours. Here, NUMA1 is linked to mesenchymal cell neoplasm.