ACTA1 and fatty liver disease: In agreement with similar findings, Escutia‐Gutiérrez et al.23discovered the significant expression of miR21a‐5p in C57BL/6J mice with metabolic‐associated fatty liver disease, along with the up‐regulation of inflammatory factors IL‐1, IL‐6, IL‐8, and TNF‐α; fibrogenic factors TGF‐β1 and α‐SMA; collagen genes; and protein levels.