The expression levels of ANRIL in PBMCs were significantly higher in the risk genotype carriers of rs10757278 and rs10811656 (GA and GG for rs10757278 and CT and TT for rs10811656) in CAD patients compared to wild type carriers (p = 0.004 and p = 0.013, respectively). This evidence concerns the gene CDKN2B-AS1 and coronary artery disorder.