TP53 and neoplasm: With the BlgCre Brca1fl/fl p53+/− Lynwt/wt and BlgCre Brca1fl/fl p53+/− Lynfl/fl comparison, only 93 significant DEGs were identified: 12 upregulated in Lynfl/fl tumours relative to Lynwt/wt tumours and 81 downregulated in Lynfl/fl tumours relative to Lynwt/wt tumours (Fig. 4A; Table S9).