Considering that the PCA group 3/4 tumours had elevated Lyn/LYN expression (Fig. 5B,C), we next assessed the overlap between the sets of significant DEGs from the BlgCre Brca1fl/fl p53+/− Lynwt/wt versus BlgCre Brca1fl/fl p53+/− Lynfl/fl comparison, the Lyn-high versus Lyn-low tumour comparison and the PCA group 3/4 versus PCA group 1/2 comparison, using Venny (https://bioinfogp.cnb.csic.es/tools/venny/) (Fig. 5F). The gene discussed is LYN; the disease is posterior cortical atrophy.