Therefore, to directly assess differences in the biology of the tumours from the cohorts, and to determine whether or not such differences were correlated with Lyn expression, we carried out an RNA-sequencing (RNAseq) analysis of tumour pieces from 39 tumours – 12 from BlgCre Brca1fl/fl p53+/− Lynwt/wt mice, 14 from BlgCre Brca1fl/fl p53+/− Lynfl/wt mice and 13 from BlgCre Brca1fl/fl p53+/− Lynfl/fl mice. The gene discussed is TP53; the disease is neoplasm.