The results confirmed that the genes were significantly differentially expressed between the Lyn-low and Lyn-high (Fig. 7A; Table S12; Fig. S7) and between the PCA group 1/2 and PCA group 3/4 tumour groups (Fig. 7B) and in expected patterns (Bcl2a1a, Cd40, Nfkb2, Relb, Il4i1, Ccl5 and Tnfaip3 were significantly more highly expressed in Lyn-high and PCA group 3/4 tumours, Shisa8 was significantly more highly expressed in Lyn-low and PCA group 1/2 tumours). The gene discussed is CD40; the disease is posterior cortical atrophy.