Consequently, when the dependent variable was whether the patient was diagnosed with ACS, the univariate logistic regression analysis demonstrated that male, age, history of smoking, hypertension and type 2 diabetes, SBP, WBC, FBG, Cys-C, UA, HDL-C, D-D, BNP, TnI, LVEF, ALT, and lg (circSCMH1/miR-874) were statistically associated with ACS occurrence. This evidence concerns the gene NPPB and Hypertension.