This study supports exercise-induced IL-6 as having potential anti-tumour properties although the complex dynamics and interactions of exercise-induced IL-6 in vivo would need to be examined and compared to the pro-inflammatory carcinogenic and immunosuppressive actions associated with long-term exposure to IL-6, which has been documented in murine models as enhancing CCR5 expression and subsequent promotion of MDSC activity (30). This evidence concerns the gene IL6 and neoplasm.