SPP1 and neoplasm: The results showed that ADM (49), CCL2 (50), CCL4 (51), CXCL3 (52), MIF (53), SPP1 (54), VEGFA (55) and VEGFB (56), which have previously been reported to promote tumor progression and metastasis, were specifically deficient in GLUL-SQSTM1- RTM (Figure 7H).