In Bb-infected cluster 2 (antigen-presenting neutrophils), immunoglobulin genes such as Iglc2, Igkv8-27, Ighv1-82, and Ighg2b were upregulated compared to the bystander cells, indicating that these neutrophils are likely involved in the activation of B and T cells following interactions with Bb. Further investigation is required to define the functional significance of this subset during Bb infection. This evidence concerns the gene IGLC2 and infection.