CEACAM5 and neoplasm: Recently, Xiaoyong et al. constructed a mouse colorectal cancer subcutaneous tumour model (n = 15), an in situ model (n = 15), and a peritoneal metastasis model (n = 10) using a CEACAM5-targeted probe to identify CRCs and resected all of the tumours under NIR-II imaging guidance, even smaller than 2 mm tumours were detected [92].