A large proportion of participants had a duration of known HIV infection (67.58%) or HAART (71.82%) less than 3 years, 23.69% had an HIV-RNA ≥ 500 IU/mL, 67.83% had a TH/TS ratio of <0.6, and only 13.47% had a CD4+ count <200 cells/μl. The gene discussed is CD4; the disease is HIV infectious disease.