CSF3 and cancer: Additionally, Pichia-produced biologics such as monoclonal antibodies targeting diseases like cancer or autoimmune disorders, growth factors like granulocyte colony-stimulating factor (G-CSF) (Pykhtina et al., 2020; Gautam et al., 2021), and antifungal proteins have shown promise in therapeutic applications (Virágh et al., 2014; Popa et al., 2019).