PLXND1 and allergic disease: In concert with the inflammatory role of immune semaphorins, Plexin-D1, and B2 in allergic diseases and concerning the effect of FP/F on the reducing expression of mentioned genes, FP/F may play a role in regulating SEMA4C, 4D, 4A and their receptors, and subsequently, modulate adverse allergic responses in AR patients compared to B/F.