By estimating StromalScore and ImmuneScore in TME, we found that TMX1, TMX3, and TMX4 exhibited a positive correlation with StromalScore (Figure 4A) and StromalScore (Figure 4B) in most cancer types, while TMX2 expression was negatively correlated with StromalScore (Figure 4A) and ImmuneScore (Figure 4B). The gene discussed is TMX1; the disease is cancer.