By estimating StromalScore and ImmuneScore in TME, we found that TMX1, TMX3, and TMX4 exhibited a positive correlation with StromalScore (Figure 4A) and StromalScore (Figure 4B) in most cancer types, while TMX2 expression was negatively correlated with StromalScore (Figure 4A) and ImmuneScore (Figure 4B). This evidence concerns the gene TMX2 and cancer.