The results of this study are similar to previous studies in demonstrating the predictive efficiency of the radiomics models for BCR4, 5, 6, 7, 8, 15 and differ from previous studies in three ways: (1) the ADC data source is heterogeneous, (2) the ROI of the model is automatically segmented, and (3) our study focuses on advanced PCa patients with non‐surgical treatment. Here, BCRP4 is linked to posterior cortical atrophy.