DPP4 and obesity due to melanocortin 4 receptor deficiency: Oxidative stress and proinflammatory processes associated with secreted cytokines and adipokines englobing TNF-α, IL-6, angiotensinogen, aldosterone-stimulating factors, aldosterone, adiponectin, dipeptidylpeptidase 4 (DPP-4), leptin, resistin, and MCP-1 arousing from dysfunctional AT have been evidenced as key players participating in obesity-related vascular dysfunction (Fleenor et al., 2022).