Median GDF15 was higher in the cancer group (N=29) at baseline (median = 614.6 pg/mL, IQR = 420.4-774.2 pg/mL) compared to the control group (N=26; median = 320.5 pg/mL, IQR = 276.6-384.1 pg/mL; p<0.001) (Figure 1). The gene discussed is GDF15; the disease is cancer.