5T4 is a 72 kDa oncofetal antigen (which is also recognized as trophoblast glycoprotein) that might be considered a qualified cancer immunotherapy target antigen as it exhibits a restricted expression profile in healthy cells, but its expression is remarkably elevated in different stages of cancer progression of different types of tumors, including ovarian cancer (75). This evidence concerns the gene TPBG and ovarian carcinoma.