Additionally, MICA alleles have been associated with higher susceptibility to inflammatory diseases, mainly autoimmune diseases, such as ankylosing spondylitis (MICA *007) (Zhou et al., 2014), Behçet’s syndrome (MICA*009 and/or *019) (Hughes et al., 2005; Munoz-Saa et al., 2006), ulcerative colitis (MICA *007), and inflammatory bowel disease with type 2 peripheral arthropathy (MICA*008) (Orchard et al., 2001). This evidence concerns the gene MICA and autoimmune disease.