On the other hand, key pro‐atherosclerotic genes including klf2 (Kruppel‐like factor 2), sele (E‐selectin), or fos (which is critical for foam cell formation and atherosclerosis[44]) all had identifiable H3K9me3 peaks and thus were repressed in DMSO treated cells only. The gene discussed is KLF2; the disease is atherosclerosis.