CGAS and angioimmunoblastic T-cell lymphoma: AITL is a major PTCL subtype characterized by intense inflammation and immune reactions, and an elevated C‐reactive protein level is a poor independent prognostic factor for AITL.[16, 17] Single‐cell RNA sequencing (scRNA‐seq) is widely used to study hematological malignancies because of its extraordinary advantages in exploring cellular heterogeneity.[18, 19, 20, 21] We performed scRNA‐seq to examine the cellular identity and investigate the expression heterogeneity of the cGAS‐STING pathway, which is closely associated with inflammation and immunity in AITL.