(He et al., 2018) established a mouse model of H. pylori infection, fed a high-fat diet (HFD) and a chow diet for six months, which showed that HFD plus H. pylori-infected mice had significantly increased abdominal circumference, fasting blood glucose (FBG), low-density lipoprotein cholesterol (LDL-C), and alanine aminotransferase (ALT) compared with HFD controls, and showed more severe hepatic steatosis, which was consistent with our hypothesis. This evidence concerns the gene GPT and Hepatic steatosis.