FGFR2 and diabetes mellitus: After Addmodule Score analysis, Fgfr1 and Fgfr2 were increased in hypertension as well as hypertension-diabetes (Figures 5H, I), respectively, but no significant changes were seen in TGF-b1, TGF-b2, and TGF-b3, the targets of Pirfenidone (Figures 5J–L).