DEGs by GH replacement in the presence of TP (i.e., TXOXTPGH) (Table S5) were functionally linked to KEGG signaling pathways associated to TCA cycle, PPAR, chemical carcinogenesis, steroid hormone biosynthesis, FA metabolism, amino acids metabolism, glycolysis/gluconeogenesis and diseases associated to glucose and lipid metabolism (e.g., NAFLD) (Table 2). The gene discussed is GH1; the disease is metabolic dysfunction-associated steatotic liver disease.