Immunohistochemistry of tumor tissue sections from patients both from Thailand (presumed OV positive) and from the UK (presumed OV negative) were positive for phosphorylated cMet, cMet receptor, phosphorylated ALK, and ALK receptor with similar intensities (Table 11, Figure 1C) compared with histologically normal tissues taken from resection margin of CCA. The gene discussed is MET; the disease is cholangiocarcinoma.