Concomitantly, a sandwich ELIZA for pro-inflammatory cytokines (TNF-α, IL-1β, IL-6 and IL-12) revealed a dose-dependent reduction in levels of pro-inflammatory cytokines (p<0.05 and p<0.001) of ART-treated tumor-bearing mice compared to the untreated tumor-bearing mice (Figure 3C). Here, TNF is linked to neoplasm.