Of the four upregulated (C2HC1A, MARCKSL1, PTGS1, CDKN2B) and five (CLEC10A, PRDX3, PRKCH, MPEG1, LMO2) downregulated genes in poor prognosis patients, several signature genes have direct or indirect roles in cancer immune environment (CLECL10A, PTGS1, C2HC1A). This evidence concerns the gene PTGS1 and cancer.